| Lupus is a condition of chronic inflammation
caused by an autoimmune disease. Autoimmune diseases are illnesses
which occur when the body's tissues are attacked by its own
immune system. The immune system is a complex system within
the body that is designed to fight infectious agents, for example,
bacteria, and other foreign invaders. One of the mechanisms
that the immune system uses to fight infections is the production
of antibodies. Patients with lupus produce abnormal antibodies
in their blood that target tissues within their own body rather
than foreign infectious agents. Lupus can cause disease of the
skin, heart, lungs, kidneys, joints, and nervous system. When
only the skin is involved, the condition is called discoid lupus.
When internal organs are involved, the condition is called systemic
lupus erythematosus (SLE).
Both discoid and systemic lupus are more common in women
than men (about eight times more common). The disease can
affect all ages but most commonly begins from age 20 to 45
years. It is more frequent in African-Americans and people
of Chinese and Japanese descent.
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