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Vesiculo-Bullous Disorders

The detection of anti-skin antibodies aids in the diagnosis and prognosis of chronic vesiculo-bullous diseases, including pemphigus, pemphigoid, mucous membrane (cicatricial) pemphigoid, and epidermolysis bullosa acquisita (EBA). Epithelial intercellular antibodies are diagnostic for pemphigus and antibodies to basement membrane antigens of stratified squamous epithelium occur in bullous pemphigoid, EBA and mucous membrane (cicatricial) pemphigoid. Serological differentiation of bullous pemphigoid from EBA can be aided by utilizing Split Skin tests.

Pemphigus
Paraneoplastic
pemphigus
Bullous pemphigoid on
split skin

Products Available

Code Product Description Determinations Product Insert
  non-CE CE
Immunofluorescence Kits
1104 IC/BMZ Skin Monkey/ Guinea Pig Esophagus 6x8 well kit 48
1105 IC/BMZ Skin Monkey Esophagus 8x6 well kit 48
1147 Monkey Esophagus/ Split Skin 48 N/A N/A
Components
2147 Monkey Split Skin for BP/EBA differentiation Slide 6 well N/A N/A
2154 ASA IC/BMZ M-Guinea Pig Esophagus 6 well slide
 6 well N/A N/A
2155 ASA IC/BMZ M-Esophagus 8 well slide
 6 well N/A N/A
2156 Rat Bladder paraneoplastic pemphigus 6 well slide 6 well N/A N/A
2200 Negative Control 0.5 ml N/A N/A
2213 IC (Monkey and Guinea Pig Esophagus) Positive Control 0.5 ml N/A N/A
2214 Pemphigus Vulgaris Positive Control 0.5 ml N/A N/A
2216 Pemphigus Foliaceus Positive Control 0.5 ml N/A N/A
2217 Basement Membrane Zone (BMZ) Positive Control 0.5 ml N/A N/A
2241 Paraneoplastic Pemphigus Positive Control 0.5 ml N/A N/A
2276 Split Skin Positive Control 0.5 ml N/A N/A
2100 IgG Conjugate 5.0 ml N/A N/A


Immunological Findings in Vesiculo-Bullous Disorders
North America: 800.537.8378 | International: 716.691.0091 | Fax 716.691.0466
60 Pineview Drive | Buffalo, NY 14228 USA